The Rams, 0-2 and without top WRs Cooper Kupp and Puka Nacua, are intent on getting RB Kyren Williams going in their home ...

The San Francisco 49ers face the Los Angeles Rams at 1:25 p.m. PDT on Sunday, Sept. 22 at SoFi Stadium in Inglewood, CA.

The San Francisco 49ers will be without All-Pro tight end George Kittle for Sunday's game against the Los Angeles Rams.

but it’s the 49ers who still have premium players at left tackle (Trent Williams), receiver (Brandon Aiyuk), linebacker (Fred Warner), cornerback (Deommodore Lenoir) and defensive end (Nick Bosa).

Earlier this week, 49ers head coach Kyle Shanahan said he doesn't ask Brock Purdy to do too much on the field. That was an understatement. Shanahan doesn't all ...

Former 49ers players Richard Sherman and Donte Whitner ripped San Francisco's defense for allowing Justin Jefferson's 97-yard ...

Add Deebo Samuel to the San Francisco 49ers’ list of injuries woes. The wide receiver will miss “a couple of weeks” due ...

Injuries are an inherent part of the game of football, and the San Francisco 49ers are feeling the effects as they prepare ...